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153,154 Studies have shown that activating GLP-1R leads to a decrease in pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-) in adipose tissue, revealing a systemic anti-inflammatory impact

The peptide may still be partly active, but degradation cannot be ruled out without analytical testing

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MT-II binds primarily to the MC1 and MC4 receptors, and to a lesser extent to MC3

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10.1038/s41419-019-1904-7 43 YueW.LiY.OuD.YangQ